How I cool children in neurocritical care
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Updated: Jun 16, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
Ericka L Fink1, Patrick M Kochanek, Robert S B Clark
1Department of Critical Care Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15224, USA. finkel@ccm.upmc.edu
Insights
Therapeutic hypothermia is being investigated to improve neurological outcomes in children with acute brain injury. This article shares a protocol for inducing hypothermia in pediatric patients following cardiac arrest.
Area of Science:
- Pediatric critical care medicine
- Neuroscience
- Emergency medicine
Background:
- Traumatic brain injury and cardiac arrest are leading causes of death in pediatric intensive care units.
- Current clinical care for pediatric brain injury is primarily supportive.
- Therapeutic hypothermia shows promise as a neuroprotective strategy in various pediatric conditions.
Purpose of the Study:
- To outline a specific protocol for inducing therapeutic hypothermia in children with acute brain injury.
- To provide a standardized approach for managing hypothermia in pediatric patients.
Main Methods:
- Targeting core body temperatures of 32-34°C.
- Utilizing cooling blankets and intravenous iced saline for rapid induction.
- Maintaining hypothermia for 24-72 hours with careful re-warming.
Main Results:
- The protocol details the methods for inducing and maintaining therapeutic hypothermia in pediatric patients.
- Vigilant re-warming is a critical component of the protocol.
Conclusions:
- This hypothermia protocol offers a structured approach for neuroprotection in pediatric acute brain injury.
- Sharing this protocol can aid other centers in implementing therapeutic hypothermia for critically ill children.
Abstract:
Brain injury is the leading cause of death in our pediatric ICU [Au et al. Crit Care Med 36:A128, 2008]. Clinical care for brain injury remains largely supportive. Therapeutic hypothermia has been shown to be effective in improving neurological outcome after adult ventricular-arrhythmia-induced cardiac arrest and neonatal asphyxia, and is under investigation as a neuroprotectant after cardiac arrest and traumatic brain injury in children in our ICU and other centers. To induce hypothermia in children comatose after cardiac arrest we target 32-34 degrees C using cooling blankets and intravenous iced saline as primary methods for induction, for 24-72 h duration with vigilant re-warming. The objective of this article is to share our hypothermia protocol for cooling children with acute brain injury.
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