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Bladder dysfunction in infants with primary vesicoureteric reflux

S Demirbag1, C Atabek, B Caliskan

  • 1Department of Paediatric Surgery, Gulhane Military Medical Academy, Ankara, Turkey. suzidemirbag@gmail.com

The Journal of International Medical Research
|February 12, 2010
PubMed

Insights

Bladder dysfunction negatively impacts spontaneous resolution of primary vesicoureteric reflux (VUR) in infants. Urodynamic testing is recommended for infants with VUR to identify these common bladder abnormalities.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Diagnostic Imaging

Background:

  • Vesicoureteric reflux (VUR) is a common condition in infants.
  • Bladder dysfunction is increasingly recognized as a factor influencing VUR outcomes.
  • Understanding the prevalence of urodynamic abnormalities in infants with primary VUR is crucial for management.

Purpose of the Study:

  • To determine the prevalence of urodynamic abnormalities in infants diagnosed with primary VUR.
  • To investigate the relationship between bladder dysfunction and the severity of primary VUR.

Main Methods:

  • Prospective review of urodynamic evaluations and medical records.
  • Analysis of data from 54 infants with primary VUR (79 ureters).
  • Categorization of bladder dysfunction based on bladder capacity.

Main Results:

  • Urodynamic dysfunction was identified in 46.3% of infants with primary VUR.
  • Low bladder capacity was observed in 35.2% and large bladder capacity in 11.1%.
  • All infants with large bladder capacity had high-grade VUR (grades IV-V).

Conclusions:

  • A significant association exists between bladder dysfunction and primary VUR in infants.
  • Urodynamic testing should be integrated into the routine clinical evaluation of infants with primary VUR.
  • Identifying bladder dysfunction can aid in predicting VUR resolution and guiding treatment.

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