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Updated: Jun 16, 2026
10:03
Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
Published on: June 27, 2025
[Pulmonary arterial hypertension in the elderly subject]
I Frachon1, A Barnier, Y Jobic
1Equipe d'accueil 3878, Groupe HTAP de Bretagne Occidentale (GETBO), IFR 148, université de Brest, CHRU de Brest, 29609 Brest, France. irene.frachon@chu-brest.fr <irene.frachon@chu-brest.fr>
Revue Des Maladies Respiratoires
|February 12, 2010
Summary
Elderly patients diagnosed with pulmonary arterial hypertension (PAH) show distinct features and a poorer prognosis. Further research is needed to optimize management strategies for this vulnerable population.
Area of Science:
- Cardiology
- Pulmonology
- Geriatrics
Context:
- Pulmonary arterial hypertension (PAH) diagnosis in elderly patients presents unique challenges.
- Limited data exists on the specific characteristics and outcomes of PAH in older adults.
Purpose:
- To delineate the clinical features of pulmonary arterial hypertension (PAH) in elderly patients (≥65 years).
- To compare the demographic, clinical, and treatment characteristics of elderly PAH patients with younger counterparts.
Summary:
- A descriptive study of 66 PAH patients revealed 24 were aged 65 and above.
- Elderly PAH patients exhibited lower mean pulmonary arterial pressure, more comorbidities, reduced 6-minute walk test distance, and higher Pro-BNP levels.
- While specific PAH treatments were administered, 15 elderly patients required long-term oxygen therapy, and their median survival was 32 months.
Impact:
- The findings highlight a poor prognosis for elderly patients with PAH.
- This study underscores the need for tailored management approaches and further investigation into optimizing treatment for older adults with PAH.
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