Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Theoretical Approaches to Psychological Disorder01:29

Theoretical Approaches to Psychological Disorder

The development of psychological disorders, which are characterized by deviant, maladaptive, and personally distressing behaviors, has been explored through several theoretical approaches.
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence, comorbidity and predictors of social anxiety severity among Chinese youth in the post-COVID-19 era.

BJPsych open·2026
Same author

From short-term benefits to developmental adaptation: effect trajectory and developmental implications of transdiagnostic sleep and circadian intervention in youth.

World journal of pediatrics : WJP·2025
Same author

Correction: The Minimal Phenomenal Experience questionnaire (MPE-92M): Towards a phenomenological profile of "pure awareness" experiences in meditators.

PloS one·2024
Same author

Are we correctly diagnosing and screening for bipolar depression?

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)·2024
Same author

[Status of Health Economics Research on Cognitive Behavioral Therapy for Insomnia].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition·2023
Same author

Distractibility, anxiety, irritability, and agitation symptoms are associated with the severity of depressive and manic symptoms in mixed depression.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)·2022
Same journal

Risk of all-cause and cause-specific mortality, and suicide attempt in people with anxiety and stress-related disorders: a systematic review, meta-analysis and meta-regression analysis of 165 studies.

World psychiatry : official journal of the World Psychiatric Association (WPA)·2026
Same journal

Artificial intelligence and the problem of physician burnout: a double-edged scalpel.

World psychiatry : official journal of the World Psychiatric Association (WPA)·2026
Same journal

The neurodiversity movement vs. the medical model of autism.

World psychiatry : official journal of the World Psychiatric Association (WPA)·2026
Same journal

The burnout paradox.

World psychiatry : official journal of the World Psychiatric Association (WPA)·2026
Same journal

Interventions in schizophrenia should be transdiagnostic, biologically informed, individualized, and disease modifying.

World psychiatry : official journal of the World Psychiatric Association (WPA)·2026
Same journal

Predicting long-term poor outcomes in individuals at clinical high risk for psychosis using real-world clinical data: the OASIS1000 prospective study.

World psychiatry : official journal of the World Psychiatric Association (WPA)·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Hypomania: a transcultural perspective.

Jules Angst1, Thomas D Meyer, Rolf Adolfsson

  • 1Psychiatric Hospital, University of Zurich, P.O. Box 68, CH-8029 Zurich, Switzerland.

World Psychiatry : Official Journal of the World Psychiatric Association (WPA)
|February 12, 2010
PubMed
Summary
This summary is machine-generated.

The Hypomania Checklist-32 (HCL-32 R1) demonstrates robust cross-cultural validity for screening hypomania. Its two-factor structure and measurement properties are largely consistent across diverse global regions.

Keywords:
HCL-32 R1,Hypomania,transcultural robustness

Related Experiment Videos

Last Updated: Jun 16, 2026

Developing a Rat Model for Bipolar Disorder
04:42

Developing a Rat Model for Bipolar Disorder

Published on: May 2, 2025

Area of Science:

  • Psychiatry
  • Cross-cultural Psychology
  • Mental Health Screening

Background:

  • Hypomania screening requires culturally robust instruments.
  • The Hypomania Checklist-32, first revised version (HCL-32 R1) is a widely used screening tool.
  • Transcultural validation is crucial for global mental health research.

Purpose of the Study:

  • To assess the transcultural robustness and measurement invariance of the HCL-32 R1.
  • To examine the HCL-32 R1's factor structure across diverse geographic regions.
  • To investigate the influence of sex and age on HCL-32 R1 scores in a multinational sample.

Main Methods:

  • Exploratory and confirmatory factor analyses were employed.
  • Data were collected from 2606 patients across twelve countries in five regions.
  • Sex and age were included as covariates in the analyses.

Main Results:

  • A two-factor structure (positive and negative hypomanic aspects) was confirmed across cultures.
  • Measurement properties of the HCL-32 R1 were largely invariant globally.
  • Subtle differences were observed in symptom frequency and factor scores across regions.

Conclusions:

  • The HCL-32 R1 is a valid and reliable screening instrument for hypomania internationally.
  • Findings support the HCL-32 R1's applicability in diverse cultural contexts.
  • The study highlights the need for culturally sensitive interpretation of screening results.