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Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
Published on: January 29, 2016
Improving patient self-management of multiple sclerosis through a disease therapy management program
Karen M Stockl1, Jennifer S Shin, Sherry Gong
1Prescription Solutions, 2300 Main St, Mail Stop CA 134-0404, Irvine, CA 92614, USA. karen.stockl@prescriptionsolutions.com
The American Journal of Managed Care
|February 13, 2010
Summary
A multiple sclerosis (MS) disease therapy management (DTM) program improved medication adherence and persistence, while reducing relapses. Patients reported better self-management skills, though quality of life and work productivity showed no significant changes.
Area of Science:
- Pharmacology
- Health Services Research
- Neurology
Background:
- Multiple Sclerosis (MS) management requires adherence to complex therapies.
- Disease Therapy Management (DTM) programs aim to improve patient outcomes.
- Integrating self-management and medication management is a key strategy.
Purpose of the Study:
- To evaluate the impact of a structured 7-month MS DTM program.
- To assess effects on medication adherence, persistence, and clinical outcomes.
- To determine patient-reported changes in self-management and quality of life.
Main Methods:
- Observational cohort study design.
- Pharmacy claims data analyzed for adherence and persistence.
- Propensity score-matched control groups (retail and specialty pharmacy patients).
- Short Form 12, Work Productivity and Activity Impairment, and MS relapse assessments.
Main Results:
- DTM patients showed significantly higher adherence compared to retail pharmacy patients.
- DTM patients demonstrated significantly greater persistence on injectable MS medications.
- A significant decrease in MS relapses was observed from baseline to 6 months.
- No significant changes in quality of life or work productivity were noted.
Conclusions:
- The MS DTM program effectively enhanced medication adherence and persistence.
- The program contributed to a reduction in multiple sclerosis relapses.
- Patients reported an improved ability to manage their health, despite no significant changes in QoL or productivity.
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