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Updated: Jun 16, 2026

A Culture Method to Maintain Quiescent Human Hematopoietic Stem Cells
Published on: May 17, 2021
Keeping courage during stem cell transplantation: a qualitative research.
Annemarie Coolbrandt1, Mieke H F Grypdonck
1University Hospitals Leuven, Department of oncology/Hematology, Leuven, Belgium. annemarie.coolbrandt@uz.kuleuven.ac.be <annemarie.coolbrandt@uz.kuleuven.ac.be>
Patients undergoing stem cell transplantation (SCT) actively create a "positive story" to maintain courage and endure treatment. This involves focusing on positive outcomes and seeking support from healthcare professionals.
Area of Science:
- Oncology
- Hematology
- Psychosocial Oncology
Background:
- Stem cell transplantation (SCT) is a demanding therapy.
- Maintaining psychological well-being is crucial for patients undergoing SCT.
Purpose of the Study:
- To explore how patients maintain courage during stem cell transplantation.
- To understand the process of enduring demanding cancer therapies.
Main Methods:
- Qualitative study utilizing a grounded theory approach.
- Data collection through participant observation and semi-structured interviews with patients and nurses.
Main Results:
- Patients actively construct a
- positive story
- to cope with SCT.
- This involves believing in a happy ending, rationalizing negative information, and seeking opportunities for a favorable outcome.
- The period of aplasia is particularly challenging, with patients relying on healthcare professionals for support.
Conclusions:
- Patients employ active strategies to maintain courage during SCT, primarily by creating a positive narrative.
- These active coping mechanisms extend beyond the passive concept of hope.
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