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Related Experiment Video

Updated: Jun 16, 2026

Efficient and Scalable Directed Differentiation of Clinically Compatible Corneal Limbal Epithelial Stem Cells from Human Pluripotent Stem Cells

Efficient and Scalable Directed Differentiation of Clinically Compatible Corneal Limbal Epithelial Stem Cells from Human Pluripotent Stem Cells

Published on: October 24, 2018

Stem cell therapies for ocular surface disease.

Sajjad Ahmad¹, Sai Kolli, Majlinda Lako

¹North East England Stem Cell Institute, Central Parkway, Newcastle upon Tyne NE13BZ, UK.

Drug Discovery Today

|February 13, 2010

Summary

This summary is machine-generated.

Corneal diseases can cause blindness by damaging the eye's outer layer. Stem cell therapies are being developed to restore vision in patients with these conditions.

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Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration

Published on: September 12, 2014

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Last Updated: Jun 16, 2026

Efficient and Scalable Directed Differentiation of Clinically Compatible Corneal Limbal Epithelial Stem Cells from Human Pluripotent Stem Cells

Efficient and Scalable Directed Differentiation of Clinically Compatible Corneal Limbal Epithelial Stem Cells from Human Pluripotent Stem Cells

Published on: October 24, 2018

Isolation and Identification of Limbal Niche Cells

Isolation and Identification of Limbal Niche Cells

Published on: October 27, 2023

Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration

Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration

Published on: September 12, 2014

Area of Science:

Ophthalmology
Regenerative Medicine
Corneal Science

Background:

Corneal transparency is crucial for vision.
Ocular surface diseases frequently cause blindness.
Disruption of the corneal epithelium leads to vision loss.

Purpose of the Study:

To review vision loss from corneal epithelium damage.
To discuss stem cell-based therapeutic strategies for corneal regeneration.

Main Methods:

Literature review of corneal diseases and stem cell therapies.
Analysis of current and emerging treatments for corneal epithelium dysfunction.

Main Results:

Corneal epithelium integrity is vital for sight.
Stem cell therapies show promise for treating corneal blindness.
Various strategies are under development to restore corneal function.

Conclusions:

Damage to the corneal epithelium is a significant cause of vision impairment.
Stem cell therapies offer a viable approach to restoring sight in patients with corneal diseases.