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Chronic lupus peritonitis with ascites
P Kaklamanis1, G Vayopoulos, G Stamatelos
1First Department of Internal Medicine, Medical School, National University of Athens, Laiko Hospital, Greece.
Annals of the Rheumatic Diseases
|March 1, 1991
Summary
Systemic lupus erythematosus can cause chronic lupus peritonitis, leading to ascites and other severe symptoms. Effective treatment involves immunosuppressants like methylprednisolone and azathioprine.
Area of Science:
- Rheumatology
- Nephrology
- Gastroenterology
Background:
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
- Lupus peritonitis is a rare but serious complication of SLE, characterized by inflammation of the peritoneum.
Observation:
- A 28-year-old woman with SLE presented with chronic lupus peritonitis, manifesting as abdominal fullness, discomfort, and ascites.
- Four months later, she developed neurological (vertigo, headaches, visual disturbances), serological, and renal (glomerulonephritis) complications.
Findings:
- The patient's lupus peritonitis and associated systemic manifestations showed a positive response to treatment.
- Treatment regimen included intravenous pulse methylprednisolone, oral azathioprine, and diuretics.
Implications:
- This case highlights lupus peritonitis as a significant manifestation of SLE requiring prompt diagnosis and management.
- Aggressive immunosuppressive therapy can effectively control lupus peritonitis and improve outcomes in SLE patients.