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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Incidence of mild cognitive impairment: a systematic review

Tobias Luck1, Melanie Luppa, Susanne Briel

  • 1Public Health Research Unit, Department of Psychiatry and Psychotherapy, Department of Mental Health, University of Leipzig, Leipzig, Germany. tobias.luck@medizin.uni-leipzig.de

Dementia and Geriatric Cognitive Disorders
|February 13, 2010
PubMed
Abstract

Insights

The incidence of mild cognitive impairment (MCI) in the elderly varies widely. Higher age, lower education, and hypertension increase the risk of developing MCI.

Area of Science:

  • Gerontology
  • Neurology
  • Epidemiology

Background:

  • Mild cognitive impairment (MCI) represents a significant risk factor for dementia development in the elderly population.
  • Understanding the incidence of MCI is crucial for clinical interest and early intervention strategies.
  • This review focuses on recent research concerning the incidence of MCI among older adults.

Purpose of the Study:

  • To systematically review and synthesize recent findings on the incidence of mild cognitive impairment (MCI) in elderly populations.
  • To identify and analyze reported incidence rates for various MCI subtypes.
  • To explore potential risk factors associated with the development of incident MCI.

Main Methods:

  • A systematic literature search was conducted to identify relevant incidence studies on MCI.
  • Inclusion criteria required studies to define 'cognitively mildly impaired' subjects using established MCI criteria.
  • Studies were selected if they employed the 'person-years-at-risk' method and utilized population- or community-based samples.

Main Results:

  • Nine studies met the inclusion criteria for the review.
  • Incidence rates for amnestic MCI subtypes ranged from 9.9 to 40.6 per 1,000 person-years.
  • Incidence rates for non-amnestic MCI subtypes were 28 and 36.3 per 1,000 person-years, with overall MCI incidence at 51 and 76.8 per 1,000 person-years.
  • Key risk factors identified for incident MCI included advanced age, lower educational attainment, and hypertension.

Conclusions:

  • The incidence rates of MCI show considerable variability across studies.
  • Analysis of potential risk factors for incident MCI was limited in the reviewed literature.
  • Standardization of MCI diagnostic criteria and their operationalization is recommended to improve consistency and comparability of findings.

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