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Updated: Jun 16, 2026

Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
Published on: January 7, 2016
A powerful new agonist: flooding the system with growth hormone
1Division of Nephrology, Department of Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA. Victoria-lim@uiowa.edu
Abstract:
Niemczyk et al. treated predialysis chronic kidney disease patients with a new growth hormone-releasing hormone agonist, AKL-0707, and noted important changes in body composition characterized by an increase in fat-free mass, a modest rise in bone mineral content, and a reduction in fat mass. These changes were accompanied by a reduction in both serum urea nitrogen and normalized protein nitrogen appearance rate, while dietary protein intake was unchanged. Importantly, there were no serious adverse events.
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