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Atopic dermatitis and ascariasis in children aged 2 to 10 years

Maria Teresa Nascimento Silva1, Valdenia M Souza, Gerson Bragagnoli

  • 1Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil, and Universidade Federal de Campina Grande (UFCG), Campina Grande, PB, Brazil. teresans@terra.com.br

Jornal De Pediatria
|February 13, 2010
PubMed

Insights

This study found that while ascariasis (Ascaris lumbricoides infection) is common in children, it is associated with a lower frequency of severe atopic dermatitis (AD). Further research is needed to understand this complex relationship.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Dermatology

Background:

  • Atopic dermatitis (AD) and ascariasis are prevalent in children from low socioeconomic areas.
  • Understanding the interplay between parasitic infections and allergic diseases like AD is crucial for public health.

Purpose of the Study:

  • To investigate the association between atopic dermatitis (AD) and ascariasis in children aged 2-10 years.
  • To determine if Ascaris lumbricoides infection influences the severity of atopic dermatitis.

Main Methods:

  • A cross-sectional study involving 1,195 children aged 2-10 years.
  • Utilized the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire and stool parasitological examination for Ascaris lumbricoides.
  • Employed multivariate logistic regression and descriptive analysis to assess associations, with relative risk (RR) and odds ratio (OR) calculated.

Main Results:

  • Prevalence of AD was 24.6% and ascariasis was 26.1% in the study population.
  • Ascaris lumbricoides infection was associated with an increased frequency of mild AD (RR = 1.7) but not severe AD when compared to children without AD.
  • In children with AD, Ascaris lumbricoides exposure was linked to a decreased frequency of the severe form of dermatitis (RR = 1.46).

Conclusions:

  • High prevalence of both atopic dermatitis and ascariasis observed in the studied population.
  • Severe atopic dermatitis appears to be related to lower Ascaris lumbricoides parasitemia.
Abstract

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