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Updated: Jun 16, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Mid-term follow-up after retrograde recanalization of chronically occluded saphenous vein graft
Alfredo R Galassi1, Salvatore D Tomasello, Luca Costanzo
1Ferrarotto Hospital, University of Catania, ETNA Foundation, Italy. argalassi@virgilio.it
Insights
A chronically occluded saphenous vein graft in a 55-year-old male was successfully recanalized using a retrograde approach. This intervention maintained graft patency and improved distal vessel diameter six months post-procedure.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Saphenous vein grafts (SVGs) are crucial for coronary artery bypass grafting (CABG).
- Ostial occlusion of SVGs presents a significant challenge in managing coronary artery disease.
- Recanalization of chronically occluded grafts is technically demanding.
Observation:
- A 55-year-old male patient presented with symptoms attributed to an occluded SVG.
- The occlusion was located at the ostium of the saphenous vein graft.
- An epicardial collateral channel was identified as a potential retrograde access route.
Findings:
- A retrograde approach via an epicardial collateral channel successfully recanalized the occluded SVG.
- Three drug-eluting stents were implanted to ensure sustained patency.
- Six-month follow-up coronary angiography confirmed the graft's patency and revealed enhancement of the distal native vessel diameter.
Implications:
- This case demonstrates the feasibility and effectiveness of retrograde recanalization for chronically occluded SVGs.
- The use of drug-eluting stents appears beneficial in maintaining long-term graft patency.
- This approach offers a potential alternative strategy for managing complex SVG occlusions.
Abstract:
We reported a case of 55-year-old male with an ostial chronically occluded saphenous vein graft which was recanalized by retrograde approach through an epicardial collateral channel with implantation of three drug eluting stents. Six-month coronary angiography showed the patency of graft and distal native vessel diameter enhancement.
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