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Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

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Related Experiment Video

Updated: Jun 16, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Rhinosinusitis and asthma.

G L Marseglia1, S Caimmi, A Marseglia

  • 1Department of Paediatrics - Foundation IRCCS Policlinico San Matteo, University of Pavia, Italy. gl.marseglia@smatteo.pv.it

International Journal of Immunopathology and Pharmacology
|February 16, 2010
PubMed
Summary
This summary is machine-generated.

Asthma and chronic rhinosinusitis are linked systemic inflammatory diseases. Evaluating and treating both upper and lower airways is crucial for managing patients with these conditions.

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Published on: January 21, 2018

Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

Related Experiment Videos

Last Updated: Jun 16, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples
11:54

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Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

Area of Science:

  • Respiratory Medicine
  • Immunology

Background:

  • Chronic rhinosinusitis (CRS) and asthma are systemic inflammatory conditions affecting the respiratory tract.
  • A correlation exists between asthma severity and CRS clinical/imaging findings.

Purpose of the Study:

  • To emphasize the need for evaluating and treating both upper and lower airways in CRS patients.
  • To highlight the importance of investigating the sinus area in moderate-to-severe asthma, irrespective of nasal symptoms.

Main Methods:

  • Review of existing literature and clinical observations.
  • Discussion on the role of nasal endoscopy in pediatric asthma patients.

Main Results:

  • CRS and asthma are interconnected, systemic inflammatory diseases.
  • Asthma severity correlates with CRS features.
  • Sinus evaluation is vital in moderate-to-severe asthma.

Conclusions:

  • Integrated upper and lower airway management is essential for CRS.
  • Nasal endoscopy is a valuable tool for detecting subclinical rhinosinusitis in asthmatic children.
  • Early diagnosis and treatment of occult sinonasal infections can improve asthma management.