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Related Concept Videos

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

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Related Experiment Video

Updated: Jun 16, 2026

Automated Joint Space Detection Improves Bone Segmentation Accuracy
06:45

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Published on: November 28, 2025

New tools for diagnosing spondyloarthropathy.

Samira Rostom1, Maxime Dougados, Laure Gossec

  • 1UPRES-EA 4058, département de rhumatologie B, faculté de médecine, hôpital Cochin, AP-HP, université Paris-Descartes, 27, rue du Faubourg-St-Jacques, 75014 Paris, France. rostomsamira2003@yahoo.fr

Joint Bone Spine
|February 16, 2010
PubMed
Summary

Diagnosing ankylosing spondylitis (AS) earlier is crucial for better management. New criteria from the Assessment of SpondyloArthritis international Society (ASAS) show promise for identifying early-stage disease, improving patient outcomes.

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Published on: December 3, 2017

Area of Science:

  • Rheumatology
  • Immunology
  • Diagnostic Imaging

Background:

  • Ankylosing spondylitis (AS) is a significant cause of chronic low back pain.
  • Current diagnostic timelines for AS range from 5-10 years, delaying crucial treatment.
  • Advancements in biotherapies and imaging offer potential for earlier detection and intervention.

Purpose of the Study:

  • To address the diagnostic delay in ankylosing spondylitis.
  • To evaluate new diagnostic criteria for early detection of AS.
  • To improve management strategies through timely diagnosis.

Main Methods:

  • Review of current diagnostic criteria for AS (New York, Amor, ESSG).
  • Evaluation of novel imaging techniques like Doppler ultrasonography and MRI.
  • Assessment of new diagnostic criteria proposed by the Assessment of SpondyloArthritis international Society (ASAS).

Main Results:

  • Existing classification criteria lack sensitivity for recent-onset AS.
  • New imaging modalities can detect early inflammatory signs.
  • ASAS criteria demonstrated good performance in a recent-onset low back pain cohort.

Conclusions:

  • Earlier diagnosis of AS is achievable with improved methods.
  • New ASAS criteria offer enhanced sensitivity for early-stage disease.
  • Timely diagnosis facilitates better management with biotherapies and improved outcomes.