Related Experiment Video
Updated: Jun 16, 2026
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Pediatric reference intervals for immunoglobulin G and its subclasses with Siemens immunonephelometric assays
Nathalie Lepage1, Shih-Han S Huang, Ed Nieuwenhuys
1Department of Pathology and Laboratory Medicine, Children's Hospital of Eastern Ontario, Ottawa, Canada.
Objective:
To determine the pediatric reference intervals for the Dade Behring IgG subclass reagents.
Design And Methods:
Blood samples of healthy children and adolescents were analyzed to determine the level of immunoglobulin G (IgG) and the IgG subclass using the reagents of Dade Behring Marburg GmbH.
Results:
The reference intervals categorized by age were reported from a total of 436 samples. There was an excellent correlation between the total IgG and the sum of the IgG subclasses.
Conclusions:
Our data provide the missing pediatric reference intervals and enable the use of the Dade Behring nephelometric IgG subclass reagents in children and adolescents.
