Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 16, 2026

Preterm EEG: A Multimodal Neurophysiological Protocol
19:32

Preterm EEG: A Multimodal Neurophysiological Protocol

Published on: February 18, 2012

Visual performance and brain structures in the developing brain of pre-term infants.

Luca Antonio Ramenghi1, Daniela Ricci, Eugenio Mercuri

  • 1NICU, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, IRCCS, University of Milan, Milan, Italy. lucrameng@hotmail.com

Early Human Development
|February 16, 2010
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a modular neonatal neurological examination: from a short screening test to a detailed assessment of specific aspects of neurological function.

European journal of pediatrics·2026
Same author

Pattern of Oculomotor Findings in Children with Attention Deficit/Hyperactivity Disorder in Relation to Methylphenidate Treatment.

Journal of clinical medicine·2026
Same author

Early neurovisual development in Dravet syndrome.

Neuroscience and biobehavioral reviews·2026
Same author

Multiple sclerosis-associated EBNA2 variants influence the response to peginterferon beta-1a therapy.

Journal of autoimmunity·2026
Same author

Early neurodevelopmental outcome in newborns with mild hypoxic-ischaemic encephalopathy.

Developmental medicine and child neurology·2026
Same author

A biomimetic model composed of injectable 3D muscle-like tissue, stromal and immune cells for recapitulating the rapid immune signature predictive of mRNA vaccine immunogenicity.

Frontiers in immunology·2025

Abnormal visual function in premature infants is linked to brain lesions and impacts cognitive development. Early identification via advanced neuroimaging and visual tests aids intervention for better outcomes.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Ophthalmology

Background:

  • Visual function in premature infants is influenced by brain lesions affecting pathways like optic radiations and occipital cortex.
  • Normal visual development relies on a complex network including cortical and subcortical areas, not just primary visual pathways.
  • Prematurity introduces unique challenges, including postnatal environment and perinatal brain lesions, that disrupt visual system development.

Purpose of the Study:

  • To investigate the relationship between structural/functional brain abnormalities and visual function in premature infants.
  • To highlight the importance of early visual function for cognitive development and the need for early intervention.
  • To explore how advanced neuroimaging techniques can enhance understanding of visual development and plasticity in neonates.

More Related Videos

How to Obtain Reliable Visual Event-related Potentials in Newborns
07:39

How to Obtain Reliable Visual Event-related Potentials in Newborns

Published on: October 24, 2019

Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

Related Experiment Videos

Last Updated: Jun 16, 2026

Preterm EEG: A Multimodal Neurophysiological Protocol
19:32

Preterm EEG: A Multimodal Neurophysiological Protocol

Published on: February 18, 2012

How to Obtain Reliable Visual Event-related Potentials in Newborns
07:39

How to Obtain Reliable Visual Event-related Potentials in Newborns

Published on: October 24, 2019

Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

Main Methods:

  • Utilizing sophisticated techniques like diffusion tensor tractography for studying brain connectivity in premature infants.
  • Combining clinical visual tests with neonatal structural and functional neuroimaging.
  • Employing age-specific tests to assess diverse visual functions, from ophthalmological aspects to visual attention and orientation processing.

Main Results:

  • Abnormal visual function correlates with lesions in specific brain areas (thalami, white matter, optic radiations) and occipital cortex involvement.
  • The integrity of a broader neural network, including frontal and temporal lobes, is crucial for normal visual development.
  • Advances in neuroimaging and specialized tests have improved the understanding of visual and visual-perceptual impairments in pre-term infants, distinguishing them from retinopathy-related issues.

Conclusions:

  • Early visual impairment in premature infants is associated with cerebral lesions and impacts cognitive development.
  • Integrated approaches using clinical assessments and advanced neuroimaging are vital for understanding early visual pathways and brain plasticity.
  • Timely identification of visual impairment enables early enrollment in crucial intervention programs, optimizing developmental trajectories.