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Related Concept Videos

Overview of Synapses01:25

Overview of Synapses

A synapse is a specialized structure where two neurons connect, allowing them to pass an electrical or chemical signal to another neuron. It is the point of communication between neurons. The term "synapse" is derived from the Greek word "synapsis," which means "conjunction." The entire process of neural communication revolves around the synapse. When activated, a neuron releases chemicals known as neurotransmitters into the synapse. These neurotransmitters cross the synapse and bind to...
Chemical Synapses01:26

Chemical Synapses

Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
Chemical Synapses01:26

Chemical Synapses

Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...

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Related Experiment Video

Updated: Jun 16, 2026

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
08:49

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention

Published on: October 16, 2013

Synapsin is selectively required for anesthesia-sensitive memory.

Stephan Knapek1, Bertram Gerber, Hiromu Tanimoto

  • 1Universität Würzburg, 97074 Würzburg, Germany.

Learning & Memory (Cold Spring Harbor, N.Y.)
|February 16, 2010
PubMed
Summary
This summary is machine-generated.

Synapsin, a key synaptic protein, is crucial for early memory formation in fruit flies. Its absence impairs anesthesia-sensitive memory (ASM) but not later memory stages.

More Related Videos

Presynaptically Silent Synapses Studied with Light Microscopy
11:02

Presynaptically Silent Synapses Studied with Light Microscopy

Published on: January 4, 2010

Related Experiment Videos

Last Updated: Jun 16, 2026

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
08:49

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention

Published on: October 16, 2013

Presynaptically Silent Synapses Studied with Light Microscopy
11:02

Presynaptically Silent Synapses Studied with Light Microscopy

Published on: January 4, 2010

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Behavioral Genetics

Background:

  • Odor-shock memory in Drosophila melanogaster exhibits complex dynamics.
  • Synaptic proteins play vital roles in memory consolidation.

Purpose of the Study:

  • To investigate the role of Synapsin in Drosophila memory formation.
  • To determine if Synapsin is essential for specific memory components.

Main Methods:

  • Utilized null mutants for Synapsin in Drosophila melanogaster.
  • Assessed memory performance using odor-shock paradigms.
  • Tested sensory-motor function and memory after cold-anesthesia exposure.

Main Results:

  • Synapsin null mutants showed deficits in early memory, not later memory.
  • Anesthesia-sensitive memory (ASM) was impaired in Synapsin mutants.
  • Synapsin deficiency did not exacerbate memory deficits in rutabaga mutants.

Conclusions:

  • Synapsin is selectively required for the formation of anesthesia-sensitive memory (ASM).
  • Synapsin-dependent mechanisms may contribute to labile memory formation via cAMP signaling.