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Developing WHO guidelines with pragmatic, structured, evidence-based processes: A case study
L W Chang1, C E Kennedy, G E Kennedy
1Cochrane HIV/AIDS Group, University of California, San Francisco, CA, USA. lchang8@jhmi.edu
Developing World Health Organization (WHO) HIV guidelines involved experts and evidence reviews. This process highlights lessons for improving future guideline development rigor and quality.
Area of Science:
- Public Health
- Evidence-Based Medicine
- Guideline Development
Background:
- Many guidelines, including those from the World Health Organization (WHO), lack rigorous methodological standards.
- Operational examples are crucial for improving the quality of future guidelines.
Purpose of the Study:
- To describe the process of developing WHO guidelines for HIV prevention and care interventions.
- To identify successes and challenges in guideline development for future improvement.
Main Methods:
- A pragmatic, structured, evidence-based approach was employed.
- Key steps included forming a committee, systematic reviews, expert identification, evidence summary distribution, and a consensus conference with voting and refinement.
- A post-conference team finalized the guidelines incorporating external feedback.
Main Results:
- A draft version of the guidelines was completed through expert consensus and refinement.
- The process identified specific successes and challenges encountered during development.
Conclusions:
- The described process offers valuable lessons for enhancing the rigor and quality of future WHO guideline development.
- Addressing identified challenges is critical for improving the overall guideline development process.
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