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Homodimeric enzymes as drug targets

D Cardinale1, O M H Salo-Ahen, S Ferrari

  • 1Dipartimento di Scienze Farmaceutiche, Università di Modena e Reggio Emilia, Via Campi 183, Modena, Italy.

Current Medicinal Chemistry
|February 17, 2010
PubMed
Summary

Targeting homodimeric enzymes is a promising therapeutic strategy. Inhibiting protein-protein interactions at enzyme interfaces offers selective drug development opportunities for various diseases.

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