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Tooth agenesis patterns in bilateral cleft lip and palate.
Theodosia N Bartzela1, Carine E L Carels, Ewald M Bronkhorst
1Department of Orthodontics and Oral Biology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
European Journal of Oral Sciences
|February 17, 2010
Summary
Tooth agenesis, a common dental anomaly, affects nearly 60% of patients with complete bilateral cleft lip and palate (BCLP). This study details agenesis patterns in BCLP patients, highlighting frequent missing teeth and common agenesis codes.
Area of Science:
- Dentistry
- Oral and Maxillofacial Surgery
- Genetics
Background:
- Individuals with cleft lip and palate (CLP) exhibit a higher incidence of dental anomalies compared to the general population.
- These anomalies can occur both within and outside the cleft area, impacting overall oral health.
- Understanding these patterns is crucial for comprehensive patient management.
Purpose of the Study:
- To determine the prevalence of tooth agenesis and patterns of hypodontia in a large cohort of patients with complete bilateral cleft lip and palate (BCLP).
- To identify the most frequently missing teeth and common agenesis patterns in this specific patient group.
Main Methods:
- Analysis of serial panoramic radiographs from 240 patients diagnosed with BCLP (ages 10.5-13.5 years at first radiograph).
- Exclusion of third molars from the evaluation of tooth agenesis.
- Application of the tooth agenesis code (TAC) to classify identified agenesis patterns.
Main Results:
- Tooth agenesis was observed in 59.8% of the evaluated BCLP patients.
- The most commonly missing teeth were upper laterals and upper and lower second premolars.
- Fifty-two distinct agenesis patterns were identified, with simultaneous agenesis of teeth 12, 22, 15, 25, 35, and 45 being the most frequent.
- Nine patients presented with BCLP and oligodontia (severe hypodontia).
Conclusions:
- Tooth agenesis is highly prevalent in patients with complete bilateral cleft lip and palate.
- Specific patterns of hypodontia, particularly involving anterior and premolar teeth, are characteristic of BCLP.
- These findings underscore the need for early and ongoing dental monitoring for individuals with BCLP to address potential hypodontia and associated complications.
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