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Related Experiment Video

Updated: Jun 16, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Published on: August 9, 2024

[Mallory-Weiss lesions].

Jeppe Lange1, Lone S Jensen

  • 1Arhus Universitetshospital, Arhus Sygehus, Kirurgisk Gastroenterologisk Afdeling L, Denmark. jeppelange@hotmail.com

Ugeskrift for Laeger
|February 17, 2010
PubMed
Summary
This summary is machine-generated.

Mallory-Weiss syndrome (MW) prognosis may be less benign than assumed. Active endoscopic therapy for bleeding stigmata in MW patients correlated with higher mortality and re-admission rates.

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Area of Science:

  • Gastroenterology
  • Surgical Endoscopy
  • Clinical Prognosis

Background:

  • Mallory-Weiss syndrome (MW) is a known condition since 1929.
  • Limited studies focus on MW lesion prognosis.
  • No prior Danish data on MW prognosis existed.

Purpose of the Study:

  • To describe patient demographics admitted with MW to a Danish surgical unit over five years.
  • To investigate the prognosis of these MW patients.

Main Methods:

  • Retrospective analysis of 49 patients with endoscopically verified MW.
  • Follow-up data collected from surviving patients.
  • Mean follow-up duration of 42.7 months.

Main Results:

  • Hemostasis achieved in all 49 patients.
  • Active endoscopic therapy group showed lower hemoglobin, higher bleeding stigmata, and more transfusions.
  • Active therapy group had significantly higher mortality (50% vs. 18%) and 10% re-admission for GI bleeding.

Conclusions:

  • A shift in attitude towards MW with bleeding stigmata is suggested.
  • The disease course may be more severe than commonly believed.
  • Further prospective studies are necessary to confirm these findings.