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Related Experiment Video

Updated: Jun 16, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

Published on: July 18, 2025

Nephrocutaneous bypass in ureteral obstruction.

Holger Gerullis¹, Thorsten H Ecke, Klaus Schwartmann

¹Department of Urology, Lukas Hospital, Neuss, Germany. holger.gerullis@gmx.net

|February 17, 2010

Summary

Nephrocutaneous bypass offers a safe urinary diversion for patients with incurable ureteral obstruction. This technique improves renal function and quality of life, providing greater mobility and independence.

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Last Updated: Jun 16, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

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A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction

Published on: December 20, 2014

Area of Science:

Urology
Surgical Procedures

Background:

Incurable ureteral obstruction presents challenges for urinary diversion.
Subcutaneous pyelovesical bypass may not be suitable for all patients.

Purpose of the Study:

To describe experiences with nephrocutaneous bypass.
To assess its role in urinary diversion for specific patient groups.

Main Methods:

Nephrocutaneous bypass performed on 15 patients with malignant or benign ureteral obstruction.
Eligibility required significant bladder/sphincter system disturbance.

Main Results:

No major perioperative complications observed.
Improved renal function and quality of life reported by all patients.
13 patients (87%) met objective criteria for "useful life".

Conclusions:

Nephrocutaneous bypass is a safe and feasible method for pyelovesical drainage.
It enhances mobility and quality of life for patients with short life expectancy.
Applicable in nonmalignant cases with careful consideration of alternatives.