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Updated: Jun 16, 2026
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A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents
Published on: July 10, 2017
Migraine in affectively ill Mexican adolescents
Steven C Dilsaver1, Franco Benazzi, Ketil J Oedegaard
1Comprehensive Doctors Medical Group, Inc., Arcadia, CA, USA.
Summary
Depressed Latino adolescents, particularly of Mexican American origin, have a significantly higher prevalence of migraine headaches. This study highlights a crucial link between major depressive episodes and migraine in this demographic.
Area of Science:
- Neuroscience
- Psychiatry
- Epidemiology
Background:
- Migraine prevalence is known to be higher in adults with depression.
- Limited research exists on migraine prevalence in adolescent populations, especially among ethnic minorities.
- Previous studies indicated higher migraine rates in adult Latino populations.
Purpose of the Study:
- To determine the prevalence of migraine headache in depressed Latino adolescents of Mexican American origin.
- To compare migraine prevalence between depressed adolescents and those with other mental disorders.
- To investigate differences in migraine prevalence between bipolar and unipolar depressed adolescents.
Main Methods:
- Cross-sectional study design.
- Inclusion of 132 consecutive Latino adolescents meeting DSM-IV criteria for major depressive episode.
- Comparison with a control group of adolescents diagnosed with other mental disorders.
- Logistic regression analysis to assess associations and control for confounders.
Main Results:
- The prevalence of migraine headache was 6 times greater in depressed Latino adolescents compared to the control group (OR = 5.98, p = 0.019).
- Migraine prevalence in this depressed adolescent group aligns with findings in adult populations.
- Unlike in adults, migraine prevalence was not significantly higher in bipolar than in unipolar depressed adolescents.
Conclusions:
- Depressed Latino adolescents exhibit a substantially elevated prevalence of migraine headache.
- The findings suggest a strong association between major depressive episodes and migraine in this specific adolescent population.
- Further research is warranted to explore the underlying mechanisms and clinical implications of this comorbidity.
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