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[The manifestations of extrapulmonary tuberculosis].
D Braumann1, K Reschofsky, K Mainzer
1II. Medizinische Abteilung, Allgemeines Krankenhaus Altona, Hamburg.
Deutsche Medizinische Wochenschrift (1946)
|April 19, 1991
Summary
A woman presented with neurological and gastrointestinal symptoms after a seizure. Diagnosis confirmed disseminated tuberculosis (tuberculosis) affecting the brain and lymph nodes, successfully treated with anti-tuberculosis medication.
Area of Science:
- Neurology
- Infectious Diseases
- Pathology
Background:
- Disseminated tuberculosis can present with diverse neurological and systemic symptoms.
- Tuberculoma formation in the brain is a serious manifestation of Mycobacterium tuberculosis infection.
Observation:
- A 27-year-old woman developed nausea, vomiting, weight loss, and cerebral lesions after a seizure.
- Biochemical tests showed elevated erythrocyte sedimentation rate and leukopenia.
- Enlarged abdominal lymph nodes and peritoneal nodules were observed.
Findings:
- Histological examination revealed caseous granulomatous inflammation consistent with tuberculosis.
- Mycobacterium tuberculosis was cultured from lymph node and peritoneal biopsy specimens.
- An intracerebral focus was confirmed as a tuberculoma after resection.
Implications:
- Early diagnosis and comprehensive anti-tuberculosis treatment, including corticosteroids, are crucial for managing disseminated tuberculosis.
- Complete resolution of cerebral and abdominal lesions was achieved with prolonged treatment.
- This case highlights the importance of considering tuberculosis in patients with unexplained neurological and systemic symptoms, especially in endemic areas.