Related Experiment Video
Updated: Jun 16, 2026

05:13
Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
[Psychoactive substance use during pregnancy: a review].
L'Encephale
|February 18, 2010
Summary
Psychoactive substance use during pregnancy is a growing public health concern, with underestimation of prevalence for alcohol and illicit drugs. Improved knowledge is crucial for targeted prevention and care.
Area of Science:
- Public Health
- Epidemiology
- Obstetrics
Context:
- Increasing psychoactive substance use during pregnancy globally presents significant public health challenges.
- Prevalence data for tobacco, alcohol, cannabis, and cocaine use during pregnancy are often underestimated or unknown, particularly in regions like France.
- Current estimation methods rely heavily on self-reported data, which may lack accuracy regarding the quantity of substances used.
Purpose:
- To highlight the underestimation of psychoactive substance use during pregnancy and the need for more accurate data collection.
- To emphasize the methodological limitations in current epidemiological studies on substance use during pregnancy.
- To underscore the importance of identifying risk factors for early detection and intervention.
Summary:
- Estimates suggest 20-30% of pregnant women use tobacco, 15% alcohol, 3-10% cannabis, and 0.5-3% cocaine.
- Prevalence of alcohol and illicit drug use during pregnancy is often unknown or underestimated, with varying methodologies and reliance on maternal interviews.
- Biological measurements in maternal blood, hair, or newborn meconium are needed for more accurate assessment.
Impact:
- Inaccurate prevalence data hinder targeted prevention campaigns and the implementation of specialized maternal and child healthcare for high-risk populations.
- Consumption of substances during pregnancy can lead to severe consequences for fetal development, including Fetal Alcohol Syndrome, a leading cause of mental retardation in France.
- Further research is essential to improve understanding and develop effective interventions for substance use during pregnancy.
Related Concept Videos
An Overview of Psychoactive Drugs
Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Substance Use Disorders Affecting Sleep
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
Hallucinogens and Psychedelics
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...
Stimulants
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
