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Postproduction Processing of Electrospun Fibres for Tissue Engineering
Published on: August 9, 2012
Heat treatment of electrospun silicate fiber substrates enhances cellular adhesion and proliferation
Tetsu Yamaguchi1, Shinji Sakai, Rie Watanabe
1Biotechnology and Food Research Institute, Fukuoka Industrial Technology Center, 1465-5 Aikawa, Kurume, Fukuoka 839-0861, Japan. tetsu@fitc.pref.fukuoka.jp
Journal of Bioscience and Bioengineering
|February 18, 2010
Abstract:
Synthetic scaffolds support cell attachment in vitro. We prepared ultra-fine silicate fibers using the sol-gel process and electrospinning, heated the fibers to 500 degrees C and investigated their effects on the behavior of human hepatocellular carcinoma (HepG2) cells. Alterations in surface composition following heat treatment improved cell adhesion and influenced cell migration.