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Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Related Experiment Video

Updated: Jun 16, 2026

An Open-Source Normothermic Perfusion System Designed for Research Scientists
11:23

An Open-Source Normothermic Perfusion System Designed for Research Scientists

Published on: July 18, 2025

CT perfusion in oncology: how to do it.

G Petralia1, L Bonello, S Viotti

  • 1Diagnostic Radiology, European Institute of Oncology, Via Ripamonte 435, 20141 Milan, Italy.

Cancer Imaging : the Official Publication of the International Cancer Imaging Society
|February 18, 2010
PubMed
Summary

Reliable computed tomography perfusion (CTp) imaging requires robust techniques and accurate data analysis. This involves precise scanner selection, contrast agent administration, and region of interest placement for detailed tumor perfusion assessment.

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Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
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Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

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Related Experiment Videos

Last Updated: Jun 16, 2026

An Open-Source Normothermic Perfusion System Designed for Research Scientists
11:23

An Open-Source Normothermic Perfusion System Designed for Research Scientists

Published on: July 18, 2025

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
09:02

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

Published on: July 31, 2016

Area of Science:

  • Medical Imaging
  • Radiology
  • Diagnostic Imaging

Background:

  • Computed Tomography Perfusion (CTp) imaging is crucial for assessing tissue perfusion.
  • Reliable CTp requires optimized scanning protocols and data analysis techniques.

Purpose of the Study:

  • To outline the essential technical and analytical considerations for robust CTp imaging.
  • To guide the optimal application of CTp for tumor assessment.

Main Methods:

  • Utilizing multislice CT scanners (16- or 64-slice) for high temporal resolution.
  • Employing dynamic scanning with a rapid bolus of iodinated contrast agent.
  • Applying breath-hold or free-breathing techniques based on the imaging region.
  • Using dedicated software for region of interest placement and kinetic modeling.

Main Results:

  • CTp imaging requires careful positioning to include the tumor and arterial supply.
  • High temporal resolution dynamic scans visualize contrast agent first pass.
  • Kinetic models generate color maps of perfusion parameters overlaid on CT images.

Conclusions:

  • Optimized CTp protocols enhance diagnostic accuracy in perfusion imaging.
  • Accurate data analysis and technique are fundamental for reliable CTp results.
  • CTp provides valuable quantitative perfusion data for tumor evaluation.