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Related Concept Videos

Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Stress and Mental Health01:30

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Psychological Responses to Stress01:20

Psychological Responses to Stress

Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
Dissociative Disorders01:27

Dissociative Disorders

Dissociative disorders represent complex psychological conditions characterized by disruptions in consciousness, memory, identity, or perception. These disruptions cause individuals to experience a disconnection from their thoughts, emotions, and memories. The phenomenon is not merely an occasional lapse in attention but a profound alteration in mental functioning that can severely impact daily life.
Dissociative Fugue
A hallmark feature of dissociative disorders is the dissociative fugue...

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Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
08:25

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

Posttraumatic stress disorder and completed suicide.

Jaimie L Gradus1, Ping Qin, Alisa K Lincoln

  • 1National Center for PTSD, VA Boston Healthcare System, Boston, MA 02130, USA. jaimie.gradus@va.gov

American Journal of Epidemiology
|February 18, 2010
PubMed
Summary
This summary is machine-generated.

Posttraumatic stress disorder (PTSD) significantly increases the risk of completed suicide. This population-based study found PTSD is a key risk factor for suicide, even after accounting for other conditions.

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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Published on: October 10, 2012

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Last Updated: Jun 16, 2026

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
08:29

Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

Published on: October 10, 2012

Area of Science:

  • Psychiatry
  • Epidemiology
  • Public Health

Background:

  • Research on posttraumatic stress disorder (PTSD) and suicide has primarily focused on ideation and attempts.
  • Limited data exist on the association between PTSD and completed suicide in population-based samples.

Purpose of the Study:

  • To examine the association between posttraumatic stress disorder (PTSD) and completed suicide.
  • To investigate PTSD as a risk factor for suicide in a large, nationwide population.

Main Methods:

  • A nested case-control study design was employed using Danish nationwide health and administrative registries.
  • Data included 9,612 suicide cases and 199,306 matched controls from 1994–2006.
  • International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) diagnoses were used.

Main Results:

  • A diagnosis of PTSD was identified in 0.40% of suicide cases and 0.05% of controls.
  • PTSD was associated with a significantly increased odds ratio for completed suicide (OR = 9.8).
  • This association persisted after controlling for psychiatric and demographic confounders (OR = 5.3), and was amplified when comorbid depression was present.

Conclusions:

  • A registry-based diagnosis of PTSD is a significant risk factor for completed suicide.
  • The findings highlight the critical need to address PTSD in suicide prevention strategies.
  • Comorbid depression further elevates suicide risk in individuals with PTSD.