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Comparison of the Relative Reactivities of the Triisopropylsilyl Group With Two Fluorous Analogs

Amador Garcia Sancho1, Xiao Wang, Bin Sui

  • 1Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.

Advanced Synthesis & Catalysis
|February 18, 2010
PubMed

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Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
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