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Updated: Jun 16, 2026
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Prostaglandin Extraction and Analysis in Caenorhabditis elegans
Published on: June 25, 2013
Preparation of the Major Urinary Metabolite of (-)-Prostaglandin E(2)
1Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716.
Tetrahedron
|February 18, 2010
Abstract:
The best way to measure whole body production of the locally acting hormone prostaglandin E(2) (PGE(2)) is to assess the accumulation of the major urinary metabolite, PGE(2) U (M). A practical preparation of this delicate diacid is described. This synthetic PGE(2)U(M) will enable production of the antibodies that will be used to quantify this key metabolite.
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