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A Conditioned Place Preference Protocol for Measuring Incubation of Craving in Rats
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Craving Predicts Within Session Drinking Behavior Following Placebo.

Robert F Leeman1, William R Corbin, Kim Fromme

  • 1Yale University School of Medicine.

Personality and Individual Differences
|February 18, 2010
PubMed
Summary
This summary is machine-generated.

Craving for alcohol, even after a placebo, predicts drinking behavior in young adults. Trait disinhibition also influences drinking, with craving partially explaining this link.

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Area of Science:

  • Psychology
  • Neuroscience
  • Addiction Research

Background:

  • Tiffany's cognitive processing model suggests alcohol craving occurs when access is blocked.
  • Understanding craving triggers is crucial for addiction treatment and prevention strategies.
  • Previous research has explored various factors influencing alcohol consumption.

Purpose of the Study:

  • To test if self-reported alcohol craving after a placebo predicts subsequent alcohol consumption.
  • To investigate if craving mediates the relationship between personality traits and alcohol intake.
  • To examine the validity of Tiffany's model in a naturalistic laboratory setting.

Main Methods:

  • Analysis of data from a laboratory alcohol challenge study with 174 moderate-to-heavy drinking young adults.
  • Focus on the placebo beverage condition to simulate partial blocking of alcohol access.
  • Measurement of self-reported craving ('wanting more alcohol') and subsequent ad libitum alcohol consumption.

Main Results:

  • Self-reports of craving following the placebo beverage significantly predicted subsequent ad libitum alcohol consumption.
  • Trait disinhibition was also a significant predictor of ad libitum consumption.
  • Craving partially mediated the association between trait disinhibition and ad libitum alcohol consumption.

Conclusions:

  • Findings support the hypothesis that craving, even in a simulated blocked-access condition (placebo), predicts alcohol consumption.
  • Craving plays a mediating role in the link between personality (disinhibition) and drinking behavior.
  • The study provides empirical support for cognitive models of alcohol craving and consumption.