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Related Concept Videos

Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Zones of Protection01:16

Zones of Protection

In power systems, the entire setup is divided into protective zones to isolate faults and protect the rest of the network. These zones include generators, transformers, buses, transmission lines, distribution lines, and motors. Each zone can be visualized as a separate room in a house, with each room protected by its own circuit breaker.
Protective zones are defined by closed dashed lines, containing one or more components. A key characteristic of these zones is the strategic placement of...
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
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Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
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Related Experiment Video

Updated: Jun 16, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

Immune zones in leprosy.

T S Rajashekar1, Gurcharan Singh, L Chandra Naik

  • 1Department of Dermatology, Sri Devaraj Urs Medical College, Tamaka, Kolar - 563 101, Karnataka, India.

Indian Journal of Dermatology
|February 18, 2010
PubMed
Summary
This summary is machine-generated.

Certain skin areas were thought immune to leprosy. However, evidence shows these "immune zones" can be affected, suggesting they are only relatively immune, not absolutely immune to leprosy development.

Keywords:
High local temperatureimmune zonesrelatively immune

Related Experiment Videos

Last Updated: Jun 16, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Microbiology

Background:

  • Leprosy (Hansen's disease) characteristically affects cooler, trauma-prone skin areas.
  • Specific skin regions, including the scalp, palms, soles, and genitalia, have been historically considered immune to leprosy lesions.

Purpose of the Study:

  • To re-evaluate the concept of
  • immune zones
  • in leprosy by examining evidence of their involvement.
  • To determine if these zones are absolutely or relatively immune to the development of leprosy.

Main Methods:

  • Review of clinical case reports.
  • Histopathological examination of affected skin.
  • Bacteriological analysis from suspected lesions.

Main Results:

  • Infrequent but documented cases of leprosy lesions in traditionally 'immune' zones exist.
  • Clinical, histological, and bacteriological evidence supports involvement in these areas.

Conclusions:

  • The so-called 'immune zones' in leprosy are not absolutely resistant.
  • These areas should be classified as 'relatively immune' rather than 'absolutely immune' to leprosy development.