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Updated: Jun 16, 2026

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

Newborn-care training and perinatal mortality in developing countries.

Waldemar A Carlo¹, Shivaprasad S Goudar, Imtiaz Jehan

¹University of Alabama at Birmingham, Birmingham, AL 35233, USA. wcarlo@peds.uab.edu

The New England Journal of Medicine

|February 19, 2010

Summary

This summary is machine-generated.

Essential Newborn Care training reduced stillbirths but did not decrease neonatal deaths in developing countries. Subsequent Neonatal Resuscitation Program training also showed no significant reduction in mortality rates.

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Published on: January 13, 2023

Area of Science:

Global Health
Maternal and Child Health
Neonatal Mortality

Background:

High rates of neonatal deaths and stillbirths occur annually, predominantly in developing nations.
There is a critical need to evaluate community-based interventions aimed at reducing these adverse outcomes.

Purpose of the Study:

To assess the impact of the World Health Organization Essential Newborn Care (ENC) course on neonatal mortality and stillbirths.
To evaluate the effectiveness of the American Academy of Pediatrics Neonatal Resuscitation Program (NRP) training in reducing neonatal and perinatal mortality.

Main Methods:

A train-the-trainer model was used to deliver ENC training to birth attendants in six developing countries.
The ENC intervention was assessed using a before-and-after study design with 57,643 infants.
The NRP intervention was evaluated via a cluster-randomized controlled trial involving 62,366 infants, focusing on the primary outcome of neonatal death within 7 days.

Main Results:

ENC training did not significantly reduce the overall neonatal death rate (RR, 0.99; 95% CI, 0.81 to 1.22) but significantly reduced stillbirths (RR, 0.69; 95% CI, 0.54 to 0.88).
NRP training, compared to control clusters, did not result in significant reductions in neonatal death, stillbirth, or perinatal death rates.

Conclusions:

Community-based Essential Newborn Care training for birth attendants did not decrease early neonatal mortality but did reduce stillbirth rates.
Additional training in Neonatal Resuscitation Program did not lead to significant improvements in neonatal or perinatal mortality rates in this setting.