Related Experiment Video
Updated: Jun 16, 2026

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure
Published on: March 12, 2020
25-year old male with pleural thickening
Abhilasha Ahuja1, D Gothi, G Amonkar
1Department of Respiratory Medicine, T. N. Medical College & B Y L Nair Hospital, Mumbai 400 008.
Differentiating lung adenocarcinomas from pseudomesotheliomatous adenocarcinoma can be challenging due to similar growth patterns. Advanced diagnostic tools like immunohistochemistry and electron microscopy are often necessary for accurate diagnosis.
Area of Science:
- Pulmonary pathology
- Oncology
- Diagnostic pathology
Background:
- Lung adenocarcinomas and malignant mesothelioma share similar growth characteristics.
- Histopathological differentiation between these conditions presents diagnostic challenges.
Purpose of the Study:
- To highlight the diagnostic difficulties in distinguishing lung adenocarcinomas from pseudomesotheliomatous adenocarcinoma.
- To emphasize the role of advanced techniques in differential diagnosis.
Main Methods:
- Comparative histopathological analysis.
- Application of immunohistochemistry.
- Utilization of electron microscopy.
Main Results:
- Similarities in growth patterns between adenocarcinomas and pseudomesotheliomatous adenocarcinoma were observed.
- Histopathology alone may be insufficient for definitive differentiation.
Conclusions:
- Accurate differentiation requires a combination of histopathology and specialized techniques.
- Immunohistochemistry and electron microscopy are crucial for resolving diagnostic ambiguities in these lung neoplasms.
Related Concept Videos
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
Pleural Disorders: Types and Brief Description
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pleura of the Lungs
Pneumothorax-II
Clinical Manifestations:
Respiratory System Abnormal Finding II: Palpation and Auscultation
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
