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Updated: Jun 16, 2026

Rapid Molecular Detection and Differentiation of Influenza Viruses A and B
Published on: January 30, 2017
Pediatric influenza
Anna M Bramley1, Joseph Bresee, Lyn Finelli
1Epidemiology and Prevention Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA.
Insights
Annual influenza epidemics cause significant illness in children, particularly younger ones. Vaccination and antiviral treatments are key strategies to prevent and manage flu complications in children aged 6 months to 18 years.
Area of Science:
- Pediatric Infectious Diseases
- Epidemiology
- Vaccinology
Background:
- Influenza viruses cause significant annual epidemics in the US.
- Pediatric morbidity from influenza includes increased outpatient visits, emergency department visits, hospitalizations, and deaths.
- Younger children and those with underlying conditions face higher risks of complications.
Purpose of the Study:
- To review the virological, clinical, and epidemiological features of seasonal influenza.
- To discuss the role of seasonal influenza vaccination in children.
- To outline the use of antiviral therapy for influenza prevention and treatment.
Main Methods:
- Review of virological data on influenza strains.
- Analysis of clinical presentations and outcomes in pediatric populations.
- Epidemiological assessment of influenza trends and impact.
- Evaluation of influenza vaccination efficacy and recommendations.
- Review of antiviral treatment guidelines and effectiveness.
Main Results:
- Influenza causes substantial annual pediatric morbidity and mortality.
- Vaccination is recommended for all children aged 6 months to 18 years.
- Antiviral treatment can reduce illness duration and complications.
Conclusions:
- Seasonal influenza remains a significant public health concern for children.
- Influenza vaccination is the most effective preventive measure.
- Antiviral therapy provides an important adjunctive treatment option.
Abstract:
Influenza viruses cause annual epidemics in the United States. Although the severity of influenza epidemics vary by season, the morbidity associated with annual influenza epidemics in children is considerable from year to year. Excess pediatric outpatient clinic visits, emergency department visits, hospitalizations, and deaths occur each influenza season and are more common among younger children and those with conditions that increase their risk for developing influenza-related complications. Vaccination is the most effective way to prevent influenza and its complications and is recommended for all children 6 months through 18 years of age. Antiviral treatment is another tool to prevent influenza and reduce the duration of illness and complications. This article will review the virological, clinical, and epidemiological features of seasonal influenza, as well as discuss seasonal influenza vaccination and antiviral therapy.
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