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Related Experiment Videos

Pharmaceuticals as hospital hazards: managing the risks.

M A McDiarmid1, H T Gurley, D Arrington

  • 1Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21205.

Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association
|February 1, 1991
PubMed
Summary

Hospitals are identifying more drugs as potential hazards to healthcare workers. A multidisciplinary team developed procedures to manage risks associated with hazardous medications beyond antineoplastic agents.

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Area of Science:

  • Occupational Health
  • Hospital Pharmacy
  • Drug Safety

Background:

  • Pharmaceuticals are increasingly recognized as biologically active chemical hazards.
  • Initial focus on antineoplastic drugs led to adoption of Occupational Safety and Health Administration (OSHA) guidelines.
  • Growing awareness necessitates review of other potentially hazardous drugs in hospital settings.

Purpose of the Study:

  • To outline a university hospital's approach to identifying and managing potentially hazardous drugs.
  • To establish a framework for evaluating drug safety beyond established hazardous categories.
  • To develop standardized handling procedures for a wider range of medications.

Main Methods:

  • Assembling a multidisciplinary committee for comprehensive drug reviews.

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  • Prioritizing drug agents based on potential risk and available toxicologic data.
  • Defining clear criteria for classifying a drug as "hazardous."
  • Developing specific handling procedures for identified hazardous drugs.
  • Requiring detailed toxicologic data for investigational drugs.

    • Main Results:

    • Implementation of a systematic process for hazardous drug identification.
    • Establishment of clear protocols for managing a broader spectrum of potentially harmful medications.
    • Enhanced worker safety through defined handling procedures.

    Conclusions:

    • A proactive, multidisciplinary approach is crucial for managing pharmaceutical hazards in hospitals.
    • Expanding the definition and management of hazardous drugs improves overall healthcare worker safety.
    • Standardized procedures are essential for mitigating risks associated with potent medications.