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Systemic lymphadenectomy cannot be recommended for low-risk corpus cancer
Takao Hidaka1, Akitoshi Nakashima, Tomoko Shima
1Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toyama, Toyama 930-0194, Japan.
Obstetrics and Gynecology International
|February 20, 2010
Summary
For low-risk endometrial cancer, omitting lymphadenectomy during hysterectomy is safe. This approach did not negatively impact disease-free survival or overall survival rates in patients.
Area of Science:
- Gynecologic Oncology
- Surgical Pathology
Background:
- Endometrial carcinoma staging often includes lymphadenectomy.
- Identifying low-risk cases may allow for less invasive surgical approaches.
Purpose of the Study:
- To evaluate the safety and efficacy of omitting lymphadenectomy in low-risk endometrial cancer.
- To determine if skipping lymphadenectomy impacts survival outcomes.
Main Methods:
- Retrospective review of 83 patients with low-risk endometrial cancer (endometrioid type, grade 1-2, <50% myometrial invasion).
- Patients underwent hysterectomy and bilateral salpingo-oophorectomy without lymphadenectomy.
- Disease-free survival (DFS), overall survival (OS), and postoperative morbidities were assessed.
Main Results:
- 5-year DFS rate was 97.6%; 5-year OS rate was 98.8%.
- No patients experienced leg lymphedema or deep venous thrombosis postoperatively.
- Omission of lymphadenectomy did not adversely affect survival outcomes.
Conclusions:
- Lymphadenectomy can be safely omitted in carefully selected low-risk endometrial carcinoma patients.
- This approach avoids unnecessary morbidity without compromising oncologic outcomes.
