Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ischemic Stroke l: Introduction

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

Ischemic Stroke ll: Pathophysiology

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

Stroke: Introduction and Types

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...

Imaging Studies VII: Vascular Imaging

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

Hemorrhagic Stroke l: Introduction

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Pragmatic Randomized Trial Comparing Surgical Clipping and Endovascular Treatment of Unruptured Intracranial Aneurysms.

AJNR. American journal of neuroradiology·2023

Same author

Continuity in ovine Johne's disease vaccination practices despite a decline in clinical disease.

Australian veterinary journal·2021

Same author

Two cases of non-parasitic splenic cysts and spleen-preserving therapy.

Annals of the Royal College of Surgeons of England·2021

Same author

Multimodal CT in Acute Stroke.

Current neurology and neuroscience reports·2019

Same author

Canadian Stroke Best Practice Recommendations for Acute Stroke Management: Prehospital, Emergency Department, and Acute Inpatient Stroke Care, 6th Edition, Update 2018.

International journal of stroke : official journal of the International Stroke Society·2018

Same author

Characterization of multiple life stages of two Australian Fasciola hepatica isolates in sheep.

Veterinary parasitology·2017

Search research articles

Related Experiment Video

Updated: Jun 16, 2026

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Published on: June 2, 2023

Acute stroke imaging. Part I: Fundamentals.

K Butcher¹, D Emery

¹Division of Neurology, University of Alberta, Edmonton, Alberta, Canada.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques

|February 23, 2010

Summary

This summary is machine-generated.

Advanced neuroimaging techniques like CT and MRI offer improved detection of acute stroke changes and blood flow, aiding in tissue salvage decisions. These methods enhance diagnosis and patient selection for reperfusion therapies such as thrombolysis.

More Related Videos

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

Related Experiment Videos

Last Updated: Jun 16, 2026

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Published on: June 2, 2023

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

Area of Science:

Neurology
Radiology
Medical Imaging

Background:

Non-contrast CT is the primary tool for stroke diagnosis but offers limited insight into tissue salvage potential.
Advanced neuroimaging techniques improve detection of acute and chronic brain changes, including ischemia and hemorrhage.

Purpose of the Study:

To review the principles of advanced CT and MRI in acute stroke diagnosis.
To discuss the utility of advanced imaging in managing acute stroke patients.
To explore patient selection for thrombolysis based on imaging data.

Main Methods:

Review of principles underlying acquisition and interpretation of advanced CT and MRI techniques.
Discussion of advanced brain parenchymal and blood flow imaging utility.
Focus on hyperacute and chronic parenchymal changes, vascular visualization, and cerebral blood flow.

Main Results:

Advanced CT and MRI enhance sensitivity for detecting ischemic and hemorrhagic changes.
These techniques visualize cerebral vasculature and blood flow, crucial for reperfusion therapy assessment.
Imaging provides prognostic information and aids in selecting patients for thrombolysis.

Conclusions:

Advanced neuroimaging modalities are crucial for acute stroke diagnosis and management.
These techniques offer superior insights into tissue salvage compared to traditional CT.
Rational patient selection for reperfusion therapies is facilitated by advanced imaging data.