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Updated: Jun 16, 2026

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
Different fetal-neonatal outcomes in siblings born to a mother with Graves-Basedow disease after total thyroidectomy:
Antonio Alberto Zuppa1, Paola Sindico, Sabrina Perrone
1Department of Pediatrics, Division of Neonatology, Catholic University of the Sacred Heart, Largo Agostino Gemelli 8, 00168 Rome, Italy. zuppaaa@rm.unicatt.it.
Introduction:
We describe three different fetal or neonatal outcomes in the offspring of a mother who had persistent circulating thyrotropin receptor antibodies despite having undergone a total thyroidectomy several years before.
Case Presentation:
The three different outcomes were an intrauterine death, a mild and transient fetal and neonatal hyperthyroidism and a severe fetal and neonatal hyperthyroidism that required specific therapy.
Conclusions:
The three cases are interesting because of the different outcomes, the absence of a direct correlation between thyrotropin receptor antibody levels and clinical signs, and the persistence of thyrotropin receptor antibodies several years after a total thyroidectomy.
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