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Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

Infection risk prevention following total knee arthroplasty.

T Levent¹, D Vandevelde, J-M Delobelle

¹Equipe opérationnelle en hygiène, polyclinique du Parc, 48, rue H.-Barbusse, 59880 Saint-Saulve, France. t_levent@ch-sa.com

Orthopaedics & Traumatology, Surgery & Research : OTSR

|February 23, 2010

Summary

Deep surgical-site infection (SSI) after total knee arthroplasty (TKA) occurred at a low incidence of 1.4%. Adherence to prevention protocols was generally good, but SSI occurrence was random regarding specific measures like antibiotic prophylaxis or MRSA screening.

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Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice

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Published on: October 16, 2014

Area of Science:

Orthopedic Surgery
Infectious Disease Prevention
Healthcare Epidemiology

Background:

Deep surgical-site infection (SSI) following total knee arthroplasty (TKA) poses a significant clinical challenge.
Mandatory prevention strategies necessitate rigorous assessment of adherence to established protocols.

Purpose of the Study:

To assess the incidence of deep SSI at 1 year post-TKA.
To evaluate adherence to skin preparation, antibiotic prophylaxis, and methicillin-resistant Staphylococcus aureus (MRSA) screening and prevention measures.

Main Methods:

Prospective study of 364 primary TKA operations (December 2005 - December 2006).
12-month follow-up for SSI incidence.
Independent assessment of adherence to antibiotic prophylaxis, skin preparation scoring, and MRSA screening/prevention.

Main Results:

Low SSI incidence of 1.4% (5/350 patients) observed.
High adherence to antibiotic prophylaxis (99%) and moderate adherence to skin preparation.
2.5% of patients were MRSA-positive, with no associated SSI development.

Conclusions:

The observed SSI incidence was low but potentially underestimated.
Good implementation of infection prevention protocols was noted.
SSI occurrence did not correlate significantly with adherence to specific prevention parameters.