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Related Experiment Video

Updated: Jun 16, 2026

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities
07:14

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities

Published on: May 24, 2022

Challenges in regenerative endodontics: a case series.

Joseph A Petrino1, Kendra K Boda, Sandra Shambarger

  • 1Division of Endodontics, University of Minnesota School of Dentistry, Minneapolis, MN 55455, USA.

Journal of Endodontics
|February 23, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...

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Revascularization effectively treats immature teeth with apical periodontitis, though it presents technical challenges. This case series offers recommendations for improving outcomes in endodontic regeneration procedures.

Area of Science:

  • Dentistry
  • Endodontics
  • Regenerative Medicine

Background:

  • Immature teeth with pulpal necrosis and apical periodontitis pose significant endodontic challenges.
  • Traditional treatments include apexification and apical barriers.
  • Revascularization presents a newer alternative treatment option.

Observation:

  • This case series reports on three patients undergoing revascularization for immature teeth with apical periodontitis.
  • The protocol involved specific irrigants, a triple antibiotic paste, and a mineral trioxide aggregate (MTA) and composite coronal seal.
  • Each case presented unique circumstances requiring tailored approaches.

Findings:

  • All six treated immature teeth showed resolution of apical periodontitis.
  • Three of the six teeth demonstrated continued root development post-treatment.

Related Experiment Videos

Last Updated: Jun 16, 2026

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities
07:14

Guided Endodontics: Three-Dimensional Planning and Template-Aided Preparation of Endodontic Access Cavities

Published on: May 24, 2022

  • Two teeth responded positively to vitality testing, indicating potential pulp survival.

    • Implications:

    • Revascularization is a technically demanding yet effective endodontic treatment for immature teeth with apical periodontitis.
    • Recommendations include using vasoconstrictor-free anesthetics, employing collagen matrices for MTA placement, informing patients about potential tooth staining (especially with minocycline), and emphasizing patient compliance.
    • These findings guide clinicians in optimizing revascularization techniques for better predictability.