[Controversies and future of the approach to cardiovascular disease in HIV patients]
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Published on: October 6, 2022
José Ignacio Bernardino de la Serna1, José Ramón Arribas López
1Unidad VIH, Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid, España. jibernardino.hulp@salud.madrid.org
Insights
Cardiovascular disease is a growing concern for people with HIV infection. Risk assessment equations are crucial for identifying patients needing interventions, regardless of the primary cause.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Context:
- Cardiovascular diseases (CVD) pose an increasing threat to patients with HIV infection.
- The etiology of elevated CVD risk in HIV-infected individuals is multifactorial, involving traditional risk factors, the virus itself, and antiretroviral therapy.
- The relative contribution of each factor to overall cardiovascular risk remains under investigation.
Purpose:
- To explore the multifactorial causes of increased cardiovascular risk in HIV-infected patients.
- To determine the most significant contributors to cardiovascular disease in this population.
- To emphasize the need for integrated cardiovascular risk assessment in HIV care.
Summary:
- Cardiovascular disease risk in HIV-infected patients is complex and multifactorial.
- The exact weight of traditional risk factors, HIV, and antiretroviral therapy is not yet fully elucidated.
- Individual patient risk is determined by a composite risk profile, necessitating routine use of cardiovascular risk equations.
Impact:
- Highlights the need for standardized cardiovascular risk assessment in HIV-infected individuals.
- Informing clinical practice to proactively manage cardiovascular health in this vulnerable population.
- Guiding future research to precisely quantify risk factors in HIV-associated cardiovascular disease.
Abstract:
Cardiovascular diseases are an increasing problem in patients with HIV infection. The causes of the increased cardiovascular risk in HIV-infected patients are multifactorial. Currently, the question of which factor has the most weight in this equation - whether traditional risk factors, the virus per se or antiretroviral therapy - remains to be determined. The absolute risk of cardiovascular disease in a particular patient depends on the composite risk profile. At present, there are no data to support a distinct approach to cardiovascular risk evaluation in HIV-infected patients. Cardiovascular risk equations should be incorporated into routine daily clinical assessment in order to identify patients in need of specific interventions.
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