Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 16, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Adaptive optics retinal scanner for one-micrometer light source.

Kazuhiro Kurokawa1, Daiki Tamada, Shuichi Makita

  • 1Computational Optics Group in the University of Tsukuba, Tsukbua, Ibaraki, Japan.

Optics Express
|February 23, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-speed full-field swept-source dynamic optical coherence tomography enabled by neural-network-based image generation.

Biomedical optics express·2026
Same author

Relaxivity Performance of Gadopiclenol Versus Gadobenate Dimeglumine In Vitro, and Liver and Brain Imaging: A Randomized Crossover Study.

Investigative radiology·2026
Same author

Dynamic full-field swept-source optical coherence tomography for high-resolution, long-depth, and intratissue-activity imaging.

Biomedical optics express·2026
Same author

SirT2 Inhibition is Associated with Improvements in Depression-like Behavior and Memory Impairment in Olfactory Bulbectomized Mice.

Molecular neurobiology·2026
Same author

<i>In vivo</i> dynamic optical coherence tomography of human skin with hardware- and software-based motion correction.

Biomedical optics express·2026
Same author

AICAR improves depression-like behaviors and is associated with hippocampal AMPK activation and modulation of neurogenesis and neuroinflammation in a microbiota disruption model.

Neurochemistry international·2026
Same journal

Denoising algorithm of Φ-OTDR systems based on adaptive fractional wavelet transform denoising.

Optics express·2026
Same journal

Millisecond photon-to-photon latency and high-speed volumetric projection system for optogenetics.

Optics express·2026
Same journal

Polarization-encoded coaxial structured light for high-precision 3D surface profilometry.

Optics express·2026
Same journal

Discrete freeform optical design based on collaborative optimization of point cloud and local normals.

Optics express·2026
Same journal

Ultrafast ghost imaging with 25 GHz speckle switching and wavelength-division multiplexing.

Optics express·2026
Same journal

Atomic vapor cells fabricated by femtosecond laser welding of standard-optical-quality glass.

Optics express·2026
See all related articles

We created an adaptive optics (AO) retinal scanner using 1-micrometer light for better deep-eye imaging. This technology enhances the observation of the photoreceptor mosaic, improving retinal imaging quality.

Area of Science:

  • Ophthalmology
  • Biomedical Optics
  • Retinal Imaging

Background:

  • 1-micrometer light offers superior deep-eye image contrast compared to 840-nm light in optical coherence tomography (OCT).
  • Adaptive optics (AO) technology can achieve high lateral resolution in retinal imaging.

Purpose of the Study:

  • To develop an adaptive optics (AO) retinal scanner utilizing a 1-micrometer light source.
  • To analyze the performance of the AO retinal scanner in AO-SLO mode for future AO-OCT development.

Main Methods:

  • Developed an AO retinal scanner with a 1-micrometer center wavelength light source.
  • Performed measurements on two normal subjects using the AO-SLO (Scanning Laser Ophthalmoscope) mode.
  • Quantified ocular aberration correction by measuring residual RMS wavefront error.

More Related Videos

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

Related Experiment Videos

Last Updated: Jun 16, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

Main Results:

  • Achieved residual RMS wavefront error below 0.1 micrometers with AO correction.
  • Demonstrated enhanced observation of the photoreceptor mosaic using the AO retinal scanner in AO-SLO mode.
  • Confirmed the potential of 1-micrometer light for improved deep retinal imaging.

Conclusions:

  • The developed AO retinal scanner effectively corrects ocular aberrations.
  • The AO retinal scanner in AO-SLO mode shows promise for advanced retinal imaging, particularly for observing the photoreceptor mosaic.
  • This work advances the development of AO-OCT systems.