Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of non-selective beta-blockers on acute kidney injury outcomes in patients with decompensated cirrhosis.

Journal of hepatology·2026
Same author

Long-Term Outcomes and Surgical Conversion After Immunotherapy in Microsatellite Instability-H Biliary Tract Cancers.

JCO precision oncology·2026
Same author

Chronic kidney disease in cirrhosis: a study of inpatients from a global perspective.

Gut·2026
Same author

United States Experience With Terlipressin in Hepatorenal Syndrome: Response, Mortality, and Transplant Outcomes - Results From the HRS Harmony Consortium.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2026
Same author

Expedited assessment for liver transplantation in patients with alcohol-associated liver disease using the Dallas consensus framework.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·2026
Same author

Screening for liver disease in patients with diabetes: new standard of care?

Proceedings (Baylor University. Medical Center)·2026

Related Experiment Video

Updated: Jun 16, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

Donor race does not predict graft failure after liver transplantation.

Sumeet K Asrani1, Young-Suk Lim, Terry M Therneau

  • 1Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

Gastroenterology
|February 24, 2010
PubMed
Summary

Donor race does not significantly predict liver graft failure after accounting for transplant center and patient factors. Race should not be used to assess donor quality in liver transplantation.

More Related Videos

Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography
09:23

Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography

Published on: September 22, 2023

Related Experiment Videos

Last Updated: Jun 16, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography
09:23

Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography

Published on: September 22, 2023

Area of Science:

  • Transplantation research
  • Organ donation science
  • Hepatology

Background:

  • Donor race has been suggested as a predictor of liver graft failure.
  • This study investigates confounding factors, such as transplant center, that may influence this association.

Purpose of the Study:

  • To evaluate the impact of transplant center and other variables on the relationship between donor race and liver graft failure.
  • To determine if donor race is an independent predictor of graft failure.

Main Methods:

  • Analysis of adult primary liver transplantation data from the Organ Procurement and Transplantation Network (2003-2005).
  • Examination of graft failure rates across different donor races: African American (AA), Caucasian, Asian/Pacific Islander (API), and other.
  • Statistical adjustments for donor and recipient factors, and stratification by transplant center.

Main Results:

  • Initially, AA, API, and other race donors showed an association with graft failure.
  • After adjusting for center and other factors, donor race was no longer a significant predictor for AA and API donors.
  • Livers from 'other' race donors remained associated with a slightly increased risk of graft failure, though not uniformly.

Conclusions:

  • Donor race is not a reliable, uniform predictor of liver graft failure.
  • The findings suggest donor race should not be used as an indicator of donor quality in liver transplantation.