[Progresses on autosomal recessive nonsyndromic mental retardation related genes]
Zhang-Yan Shi1, Fu-Chang Zhang, Xiao-Cai Gao
1College of Life Science, Institute of Population and Health, Northwest University, Xi'an 710069, China. kjshi@nwu.edu.cn
Abstract:
Some autosomal genes are associated with development and function of nervous system. Mutations of these genes can lead to nonsyndromic mental retardation. This paper reviews recent progresses on autosomal recessive nonsyndromic mental retardation related genes, including localization, expression, biological function and pathogenesis after mutations. The prospect in this field is also discussed.
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