Related Experiment Video
Updated: Jun 16, 2026
04:08
Evaluation of the Effectiveness of Longitudinal Incision for Endoscopic Submucosal Excavation of Gastric Subepithelial Lesions
Published on: April 28, 2026
Characteristics indicating adenomyosis coexisting with leiomyomas: a case-control study.
F Andrei Taran1, Amy L Weaver, Charles C Coddington
1Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Mayo Clinic, 200 First St., SW, Rochester, MN 55905, USA. andrei.taran@med.ovgu.de
Human Reproduction (Oxford, England)
|February 24, 2010
Summary
Women with both adenomyosis and uterine leiomyomas often experience more pelvic pain and have a lower fibroid burden. These distinct clinical features can aid in diagnosing adenomyosis alongside leiomyomas before hysterectomy.
Area of Science:
- Gynecology
- Pathology
- Women's Health
Background:
- Adenomyosis is frequently diagnosed post-hysterectomy and often co-occurs with uterine leiomyomas.
- Distinct clinical features differentiating concurrent adenomyosis and leiomyomas require identification for improved diagnosis.
Purpose of the Study:
- To identify specific clinical characteristics associated with a concurrent diagnosis of adenomyosis in women presenting with uterine leiomyomas.
Main Methods:
- A case-control study involving women undergoing hysterectomy.
- Retrospective review of medical records to collect sociodemographic, anthropometric, intraoperative, and pathologic data.
Main Results:
- The study included 255 patients: 85 with adenomyosis and leiomyomas, 170 with leiomyomas only.
- Concurrent adenomyosis was associated with increased pelvic pain (OR 3.4), reduced fibroid burden (OR 0.6), higher parity (OR 3.8), and lower BMI (OR 0.8).
Conclusions:
- Concurrent adenomyosis and leiomyomas present unique clinical profiles compared to leiomyomas alone.
- Significant pelvic pain with a smaller fibroid burden may indicate concomitant adenomyosis.
Related Concept Videos
01:19Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
01:16Uterine Tubes
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...