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Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

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Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst
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Published on: March 31, 2023

Infantile epididymitis with calcification.

Katsumi Muramori1, Koji Nagata, Noritoshi Handa

  • 1Division of Pediatric Surgery, Oita Prefectural Hospital, 476 Bunyou Oita, Japan.

Journal of Indian Association of Pediatric Surgeons
|February 24, 2010
PubMed
Summary

Calcifying chronic epididymitis in an infant, a rare condition, was diagnosed using serial ultrasound, avoiding unnecessary surgery. This case highlights the importance of imaging in differentiating infantile scrotal masses.

Keywords:
Infantile epididymitis calcification

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Published on: December 12, 2025

Area of Science:

  • Pediatric Urology
  • Medical Imaging
  • Neonatal Pathology

Background:

  • Infantile epididymitis is considered rare, with limited reported cases in medical literature.
  • Calcification within chronic epididymitis in infants has not been previously documented.
  • Scrotal calcification in infants often raises suspicion for malignancy, necessitating careful differential diagnosis.

Observation:

  • A 1-month-old infant presented with symptoms suggestive of scrotal pathology.
  • Serial ultrasound examinations were crucial in identifying a calcified lesion adjacent to the normal testis.
  • Tumor markers, including alpha-fetoprotein (AFP) and Human Chorionic Gonadotropin beta (HCG beta), were within normal physiological ranges.

Findings:

  • The case presented is the first reported instance of calcifying chronic epididymitis in an infant.
  • Ultrasound findings allowed for the differentiation of the calcified lesion from testicular torsion and neoplasm.
  • The absence of elevated tumor markers further supported a benign diagnosis.

Implications:

  • This case underscores the utility of serial ultrasound in the diagnosis of infantile scrotal conditions.
  • Accurate imaging can prevent unnecessary surgical interventions, such as orchiectomy, in infants.
  • The findings expand the differential diagnosis for scrotal calcifications in neonates, including rare inflammatory conditions.