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Published on: August 30, 2019
Pulmonary injury after intravenous hydrocarbon injection
1Pediatric Intensive Care Unit, Departments of Pediatrics, Sainte-Justine Hospital, Université de Montréal, Montréal, Québec.
Insights
Intravenous hydrocarbon injection can cause severe, yet reversible, pulmonary edema. This case highlights a young man
Area of Science:
- Toxicology
- Pulmonary Medicine
- Case Reports
Background:
- Hydrocarbon ingestion is a common cause of poisoning.
- Intravenous injection of hydrocarbons is rare and poorly documented.
- Pulmonary complications following hydrocarbon injection are not well understood.
Observation:
- An 18-year-old male presented with acute chest pain, cough, and progressive dyspnea.
- Initial investigations revealed severe metabolic acidosis and pulmonary edema on chest radiograph.
- The patient reported self-injection with Varsol, a hydrocarbon mixture, prior to symptom onset.
Findings:
- Intravenous hydrocarbon injection led to acute, reversible pulmonary edema.
- The patient's respiratory status and chest radiograph normalized within 7 days.
- This case demonstrates a direct link between intravenous hydrocarbon administration and pulmonary injury.
Implications:
- Highlights a potential route of severe pulmonary toxicity from hydrocarbon abuse.
- Suggests prompt recognition and supportive care are crucial for managing hydrocarbon-induced pulmonary edema.
- Underscores the need for awareness among healthcare professionals regarding non-traditional routes of substance abuse and their consequences.
Abstract:
This report describes the case of a young man in whom an intravenous injection of a hydrocarbon led to reversible pulmonary edema. An 18-year-old male presented with chest pain, a cough and progressive dyspnea at a multidisciplinary paediatric intensive care unit in a tertiary care university hospital. Six hours after oxygen was given, blood gases were pH 7.16, partial pressure of carbon dioxide 43 torr (5.7 kPa), partial pressure of arterial oxygen 149 torr (19.9 kPa) and bicarbonate concentration 15 mEq/L. A chest radiograph suggested pulmonary edema. On day 3, the patient stated that he had injected himself with Varsol (Imperial Oil, Canada) - a mixture of straight and branched-chain hydrocarbons, naphthenes and alkyl derivatives of benzene - several hours before his admission. On day 5, the patient's respiratory rate returned to 20 breaths/min, and his chest radiograph was normal by day 7. The present case report suggests that the intravenous injection of hydrocarbons may lead to reversible pulmonary injury.
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