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Related Experiment Video

Updated: Jun 15, 2026

Continuous Video Electroencephalogram during Hypoxia-Ischemia in Neonatal Mice

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Published on: June 11, 2020

Electrolyte status in birth asphyxia.

Pallab Basu¹, Sabyasachi Som, Harendranath Das

¹Department of Biochemistry, Burdwan Medical College and Hospital, Burdwan, West Bengal, India. basu_pallab@yahoo.co.in

Indian Journal of Pediatrics

|February 24, 2010

Summary

Neonatal asphyxia is linked to early hyponatremia and hypocalcemia, with electrolyte levels correlating to asphyxia severity. Potassium levels were also elevated in affected newborns.

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Published on: June 21, 2024

Area of Science:

Neonatalogy
Pediatric Medicine
Biochemistry

Background:

Neonatal asphyxia is a critical condition affecting newborns.
Electrolyte imbalances are common in neonates experiencing birth asphyxia.
Understanding these imbalances is crucial for timely intervention.

Purpose of the Study:

To investigate electrolyte status (sodium, potassium, calcium) in newborns with varying degrees of asphyxia.
To compare electrolyte levels in asphyxiated newborns with a control group.
To correlate electrolyte levels with the severity of neonatal asphyxia.

Main Methods:

Serum samples were collected from asphyxiated newborns and controls immediately after birth.
Levels of sodium, potassium, and total calcium were measured.
Statistical analysis was performed to compare groups and assess correlations.

Main Results:

Asphyxiated newborns showed significantly lower serum sodium (122.1 mEq/L vs 138.8 mEq/L) and calcium (6.85 mg/dl vs 9.50 mg/dl) levels.
Mean serum potassium was higher in asphyxiated newborns (5.05 mEq/L vs 4.19 mEq/L).
Electrolyte levels correlated with Apgar scores, indicating a direct relationship with asphyxia severity.

Conclusions:

Hyponatremia and hypocalcemia develop early and concurrently in neonatal asphyxia.
The severity of hyponatremia and hypocalcemia is directly proportional to the degree of asphyxia.
Elevated serum potassium, though within normal limits, also correlates with asphyxia severity.