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Effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) application on enamel microhardness after
Sule Bayrak1, Emine Sen Tunc, Isil Saroglu Sonmez
1Department of Pediatric Dentistry, Faculty of Dentistry, Ondokuz Mayis University, 55139 Samsun, Turkey. suleb76@yahoo.com
American Journal of Dentistry
|February 25, 2010
Summary
Casein phosphopeptide-amorphous calcium phosphate (CCP-ACP) significantly increased bleached enamel microhardness. Fluoride treatments showed no significant changes, indicating CCP-ACP is more effective for remineralization after bleaching.
Area of Science:
- Dental Materials Science
- Biomaterials Research
- Enamel Microhardness Testing
Background:
- Dental bleaching procedures, particularly with hydrogen peroxide (HP), can negatively impact enamel microhardness.
- Restorative treatments are crucial to mitigate post-bleaching enamel demineralization and surface changes.
- Assessing the efficacy of remineralizing agents like CCP-ACP and fluoride compounds is vital for clinical dental practice.
Purpose of the Study:
- To evaluate the effect of casein phosphopeptide-amorphous calcium phosphate (CCP-ACP) on the microhardness of bleached enamel.
- To compare the efficacy of CCP-ACP with traditional fluoride applications in restoring enamel microhardness after bleaching.
Main Methods:
- Bovine incisor enamel sections were subjected to three bleaching cycles using 38% hydrogen peroxide.
- Treated groups included bleaching only, bleaching with daily CCP-ACP paste, bleaching with casein phosphopeptide-amorphous calcium fluoride phosphate (CPP-ACPF) paste, bleaching with sodium fluoride (NaF) solution, and bleaching with APF gel.
- Vickers microhardness testing was performed before and after treatments, with specimens kept in artificial saliva.
Main Results:
- Enamel microhardness significantly increased in groups treated with CCP-ACP (Group B) and CPP-ACPF (Group C) (P < 0.001).
- No significant microhardness changes were observed in the bleaching-only group (Group A), NaF group (Group D), or APF gel group (Group E) (P > 0.05).
- Statistical analysis revealed significant differences in microhardness changes among groups, with CCP-ACP demonstrating the highest increase.
Conclusions:
- Daily application of CCP-ACP paste effectively enhances the microhardness of bleached enamel.
- CCP-ACP demonstrates superior efficacy compared to tested fluoride agents in remineralizing enamel following hydrogen peroxide bleaching.
- These findings suggest CCP-ACP as a promising agent for managing dental enamel after bleaching procedures.
